DETROIT (AP) — Aretha Franklin, the undisputed "Queen of Soul" who sang with matchless style on such classics as "Think," ''I Say a Little Prayer" and her signature song, "Respect," and stood as a cultural icon around the globe, has died at age 76 from advance pancreatic cancer.

Publicist Gwendolyn Quinn tells The Associated Press through a family statement that Franklin passed Thursday at 9:50 a.m. at her home in Detroit. The statement said "Franklin's official cause of death was due to advance pancreatic cancer of the neuroendocrine type, which was confirmed by Franklin's oncologist, Dr. Philip Phillips of Karmanos Cancer Institute" in Detroit.

The family added: "In one of the darkest moments of our lives, we are not able to find the appropriate words to express the pain in our heart. We have lost the matriarch and rock of our family."

The whole world will miss her but will always rejoice in her remarkable legacy. The Queen is dead. Long live the Queen. #RIPArethaFranklin

Elton xx

— Elton John (@eltonofficial) August 16, 2018

Let’s all take a moment to give thanks for the beautiful life of Aretha Franklin, the Queen of our souls, who inspired us all for many many years. She will be missed but the memory of her greatness as a musician and a fine human being will live with us forever. Love Paul pic.twitter.com/jW4Gpwfdts

— Paul McCartney (@PaulMcCartney) August 16, 2018

I just arrived at Aretha Franklin’s childhood home.

Many people have dropped off flowers to honor the Queen of Soul @wtva9news pic.twitter.com/MPt7bbqepX

— Shanté Sumpter (@shantewtva9) August 16, 2018