Low-dose aspirin can reduce the risk of ICU admission and death of Covid-19, researchers say

Low-dose aspirin may help protect the lungs and reduce the need to put patients on ventilators, researchers reported Wednesday.The cheap and widely av...

Posted: Mar 18, 2021 1:54 PM
Updated: Mar 18, 2021 2:45 PM

Low-dose aspirin may help protect the lungs and reduce the need to put patients on ventilators, researchers reported Wednesday.

The cheap and widely available pills also keep patients out of ICUs and can reduce the risk of death, probably by preventing tiny blood clots, a team at George Washington University reported in a study published in the journal Anesthesia & Analgesia.

Aspirin is particularly attractive because it is one of the most widely available over-the-counter drugs. Its cost, at just cents per dose, is minuscule compared with other commonly used anti-Covid drugs such as remdesivir, which can run thousands of dollars for a typical treatment course.

Aspirin can help prevent blood clots, which is why people who have had a heart attack are often advised to take a baby aspirin every day.

'The reason why we started looking at aspirin and Covid is because in the spring we all realized that all these patients started to have a lot of thrombotic complications, or a lot of blood clots that have formed throughout their bodies,' Dr. Jonathan Chow, assistant professor of anesthesiology and critical care medicine at the George Washington School of Medicine and Health Sciences, told CNN.

'That is why we thought that using an antiplatelet agent, or a blood thinner, like aspirin, might be helpful in Covid-19,' Chow said.

The team looked at the records of 412 patients admitted to several US hospitals between March and July 2020. About 24% of the patients received aspirin within 24 hours of hospital admission, or in the seven days before hospital admission. But most, 76%, did not receive the drug. Aspirin use was associated with a 44% reduction in mechanical ventilation, a 43% reduction in ICU admission, and a 47% reduction for in-hospital mortality, the researchers found.

Other studies have made similar findings. One study, published in the journal PLOS One, looked at more than 30,000 US veterans with Covid-19, and found those already taking aspirin had half the risk of dying as those not prescribed the daily pills.

Chow cautioned that one limitation of his team's new study was that it looked at medical records and did not randomly assign patients to take either aspirin or a placebo.

He pointed to the Recovery Trial in the United Kingdom, which is investigating aspirin and Covid-19 in a gold standard randomized control trial, as the ultimate arbiter in whether aspirin definitively improves outcomes as compared with patients who don't take the drug.

Mississippi Coronavirus Cases

Data is updated nightly.

Cases: 512632

Reported Deaths: 10262
CountyCasesDeaths
Harrison34853555
DeSoto33162432
Hinds32556641
Jackson24830389
Rankin22442402
Lee16238242
Madison14874283
Jones14086247
Forrest13741259
Lauderdale12249324
Lowndes11286193
Lamar10644140
Pearl River9707244
Lafayette8827143
Hancock7835132
Washington7550169
Oktibbeha7204138
Monroe6989179
Pontotoc6970109
Warren6849178
Panola6746134
Neshoba6726210
Marshall6653141
Bolivar6440151
Union633897
Pike5924156
Alcorn5862107
Lincoln5525136
George510180
Prentiss500884
Tippah490282
Itawamba4829107
Scott477499
Adams4766125
Tate4748116
Leflore4723144
Copiah455895
Yazoo455591
Simpson4543117
Wayne442772
Covington432895
Sunflower4299106
Marion4265112
Coahoma4227109
Leake413790
Newton395581
Tishomingo381793
Grenada3775109
Stone365666
Jasper340166
Attala337790
Winston317792
Chickasaw313367
Clay311878
Clarke301195
Calhoun284449
Holmes271289
Smith268952
Yalobusha243747
Tallahatchie231453
Greene224749
Walthall221366
Lawrence217840
Perry213356
Amite209557
Webster205148
Noxubee188642
Montgomery181557
Carroll174441
Jefferson Davis173643
Tunica163239
Benton152639
Kemper144941
Choctaw136527
Claiborne134238
Humphreys131139
Franklin124929
Quitman107528
Wilkinson105939
Jefferson96834
Sharkey65121
Issaquena1957
Unassigned00

Alabama Coronavirus Cases

Cases: 844951

Reported Deaths: 16115
CountyCasesDeaths
Jefferson1161002006
Mobile741871379
Madison53279732
Shelby38325368
Baldwin38068589
Tuscaloosa36009641
Montgomery34482781
Lee25550263
Calhoun22585518
Morgan22451406
Etowah20013517
Marshall18777316
Houston17727425
St. Clair16875358
Limestone16135218
Cullman16044303
Elmore15904294
Lauderdale14968306
Talladega14189299
DeKalb12967269
Walker12020380
Blount10714192
Autauga10517157
Jackson10157194
Coffee9414192
Colbert9334208
Dale9018191
Tallapoosa7254201
Russell707765
Chilton7018170
Escambia6955143
Covington6932195
Franklin6340108
Chambers5783142
Marion5401130
Dallas5285209
Pike5118109
Clarke484986
Lawrence4826129
Winston4780110
Geneva4642136
Bibb434094
Barbour369480
Butler3434100
Marengo342393
Monroe337066
Randolph334367
Pickens333188
Fayette330085
Henry320666
Hale318189
Cherokee317563
Crenshaw260477
Washington256952
Cleburne254460
Lamar251253
Clay250869
Macon244764
Conecuh192762
Coosa184947
Lowndes178168
Wilcox177438
Bullock152645
Perry141840
Sumter139241
Greene130245
Choctaw93228
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