Ebola continues to ravage northeastern Congo

Ebola virus disease has sickened 188 people and killed 118 in the Democratic Republic of Congo's northeaster...

Posted: Oct 10, 2018 8:54 AM
Updated: Oct 10, 2018 8:54 AM

Ebola virus disease has sickened 188 people and killed 118 in the Democratic Republic of Congo's northeastern region, the World Health Organization reported Monday.

Of the total cases, 153 have been confirmed, and 35 are probable. Fifty-one people have survived the disease, according to WHO, the United Nations' public health division.

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Tedros Adhanom Ghebreyesus

On average, Ebola -- which causes fever, severe headache and in some cases hemorrhaging -- kills about half of those infected, but case fatality rates in individual outbreaks have varied from 25% to 90%.

'An outstanding job'

"The response to the outbreak is being led by the government of the DRC, which is doing an outstanding job in an extremely difficult situation," Dr. Tedros Adhanom Ghebreyesus, director-general of WHO, said at a UN Security Council meeting last week. He added that WHO has more than 200 staffers on the ground, operating out of four hubs and partnering with other organizations.

"We are now at a critical point in the outbreak," he said.

Fifty-two patients have received experimental Ebola treatments during this outbreak, Dr. Peter Salama, WHO's deputy director-general of emergency preparedness and response, tweeted on Saturday.

Four treatments may be administered under a compassionate use framework, with doctors deciding the best treatment for each patient based, in part, on the complexity of administering and monitoring the drug, according to WHO.

"This is the first time in history that treatments are being used at scale during an outbreak, providing hope for people with the disease," Salama tweeted.

Only two of the treatments are favored: ZMapp, an experimental treatment developed by San Diego-based Mapp Biopharmaceutical Inc., and remdesivir, an antiviral drug developed by Gilead Sciences Inc. in collaboration with the US Centers for Disease Control and Prevention and the US Army Medical Research Institute for Infectious Diseases.

A third drug, REGN3470-3471-3479, is in the early stages of development, and there is "uncertainty" about whether a fourth drug, favipiravir, provides benefit to patients, according to WHO.

Complicating factors

North Kivu province is the epicenter of the current outbreak, though some cases have been reported in neighboring Ituri province, according to WHO. The two provinces, which are among the most populated in the nation, border Uganda, Rwanda and South Sudan.

Ebola most commonly affects people and nonhuman primates, such as monkeys, gorillas and chimpanzees. This is the second outbreak in Congo this year, according to WHO. A previous outbreak began in May and ended in July; it affected a western region of the country, where 54 cases were recorded, including 33 deaths.

Beginning with the 1976 discovery of Ebola in an area that is now the Democratic Republic of Congo, the country has experienced 10 outbreaks, including this year's outbreaks.

Congo is also experiencing a long-term humanitarian crisis that includes intermittent armed conflict, according to WHO. Other health epidemics, including cholera, measles and polio, as well as human trafficking, are flourishing there. WHO has estimated that more than 1 million refugees and internally displaced people are in North Kivu and Ituri, and their movement through and out of the provinces is a potential risk factor for the spread of Ebola.

Tedros noted an increase increase in the frequency and intensity of attacks by armed groups as a hindrance in stopping the outbreak.

On Thursday, three Red Cross volunteers were injured during a burial service in the city of Butembo, according to the International Federation of the Red Cross. Two suffered serious injuries.

Last week, a delegation from Congo participated in a meeting that brought together representatives from Uganda, Burundi, South Sudan, Tanzania, Kenya and Rwanda, Congo's Ministry of Health reported on Sunday.

The meeting, which took place in Entebbe, Uganda, focused on the measures to be taken to prevent the spread of the Ebola epidemic. The nations worked to develop an action plan to further develop their emergency preparedness and disease response mechanisms, the ministry said.

Since the start of a vaccination program August 8, 14,869 people have been vaccinated in Congo, according to the Ministry of Health. The experimental rVSV-ZEBOV vaccine, made by pharmaceutical company Merck, proved highly protective against the deadly virus in a major trial in Guinea, according to WHO.

Two barriers faced by the health workers include the security situation and "pockets of community mistrust, especially around a village called Ndindi, which is where many of the most recent cases have occurred," Tedros said.

"Small but significant numbers of people refuse active followup or refuse to be treated in the Ebola treatment units," he said. "We are working closely with religious leaders, youth and women's groups and with the families themselves to overcome this obstacle."

Mississippi Coronavirus Cases

Data is updated nightly.

Cases: 319948

Reported Deaths: 7371
CountyCasesDeaths
DeSoto22285267
Hinds20719421
Harrison18431317
Rankin13901282
Jackson13718248
Madison10263224
Lee10059176
Jones8467167
Forrest7832153
Lauderdale7261242
Lowndes6517150
Lamar635188
Lafayette6313121
Washington5425137
Bolivar4841133
Panola4670110
Oktibbeha466198
Pearl River4605147
Marshall4574105
Warren4440121
Pontotoc425873
Monroe4157135
Union415777
Neshoba4063179
Lincoln4008112
Hancock386987
Leflore3515125
Tate342486
Sunflower339491
Pike3371111
Alcorn327272
Scott320374
Yazoo314171
Adams308086
Itawamba305178
Copiah299966
Coahoma298784
Simpson298589
Tippah291968
Prentiss284161
Leake272074
Marion271280
Covington267283
Wayne264642
Grenada264087
George252251
Newton248663
Tishomingo231868
Winston230181
Jasper222148
Attala215073
Chickasaw210559
Holmes190474
Stone188433
Clay187954
Tallahatchie180041
Clarke178980
Calhoun174132
Yalobusha167840
Smith164134
Walthall135347
Greene131834
Lawrence131124
Montgomery128643
Noxubee128034
Perry127238
Amite126242
Carroll122330
Webster115032
Jefferson Davis108234
Tunica108127
Claiborne103130
Benton102325
Humphreys97533
Kemper96629
Franklin85023
Quitman82216
Choctaw79118
Wilkinson69632
Jefferson66228
Sharkey50917
Issaquena1696
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Alabama Coronavirus Cases

Cases: 548657

Reported Deaths: 11306
CountyCasesDeaths
Jefferson810031566
Mobile42105831
Madison35690525
Tuscaloosa26173458
Shelby25607254
Montgomery25081614
Baldwin21868314
Lee16278176
Calhoun14719327
Morgan14629285
Etowah14175364
Marshall12453230
Houston10781287
Elmore10293214
Limestone10179157
St. Clair10162251
Cullman9952201
Lauderdale9603250
DeKalb8972190
Talladega8460184
Walker7338280
Autauga7241113
Blount6945139
Jackson6932113
Colbert6413140
Coffee5635127
Dale4928116
Russell454841
Chilton4476116
Franklin431382
Covington4275122
Tallapoosa4138155
Escambia401680
Chambers3728124
Dallas3607158
Clarke353061
Marion3240107
Pike314378
Lawrence3133100
Winston283472
Bibb268564
Geneva257981
Marengo250565
Pickens236962
Barbour234559
Hale227278
Butler224271
Fayette218862
Henry194543
Randolph187544
Cherokee187345
Monroe180041
Washington170539
Macon163051
Clay160059
Crenshaw155957
Cleburne153444
Lamar146837
Lowndes142254
Wilcox126930
Bullock124342
Conecuh113630
Coosa111729
Perry108626
Sumter105732
Greene93634
Choctaw62125
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