Here is a look at the life of US Senator John McCain.
Birth date: August 29, 1936
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Death date: August 25, 2018
Birth place: Panama Canal Zone
Birth name: John Sidney McCain III
Father: John McCain Jr., Navy admiral
Mother: Roberta (Wright) McCain
Marriages: Cindy (Hensley) McCain (May 17, 1980-August 25, 2018, his death); Carol (Shepp) McCain (1965-1980, divorced)
Children: with Cindy (Hensley) McCain: Bridget, James, John and Meghan; with Carol (Shepp) McCain: Sidney, Andrew (Adopted from her previous marriage) and Douglas (Adopted from her previous marriage)
Education: US Naval Academy, 1958
Military service: US Navy, 1958-1981, Captain
Religion: Raised Episcopalian
Was awarded the Silver Star, the Bronze Star, the Legion of Merit, a Purple Heart and the Distinguished Flying Cross.
McCain's father and grandfather were both four-star US Navy admirals. They were the first father and son to achieve this rank.
1977-1981 - Navy liaison to the US Senate.
1981 - Retires from the US Navy.
1983-1987 - US Representative from Arizona's 1st District.
November 4, 1986 - Wins the US Senate seat vacated by retiring Senator Barry Goldwater.
1989-1991 - Is investigated as being one of five senators, called the Keating Five, who interfered with regulators on behalf of Charles Keating, a financier accused of financial violations and convicted of securities fraud. McCain is cleared, but the Senate Ethics Committee decides that McCain showed poor judgment in his efforts for Keating, who was a large contributor to McCain's campaign.
1990s - As part of the Senate Select Committee on POW/MIA Affairs, McCain works with Democrats, including John Kerry, on normalizing relations and increasing trade with Vietnam.
November 3, 1992 - Is re-elected to the Senate.
1993 - McCain has a melanoma lesion removed from his left shoulder. It is declared Stage 0, of little long-term concern.
November 3, 1998 - Is re-elected to the Senate.
1999 - McCain's memoir, "Faith of My Fathers," is published.
September 27, 1999 - Formally announces his presidential candidacy, while in New Hampshire.
March 9, 2000 - Suspends his campaign for president.
May 9, 2000 - Endorses George W. Bush for president.
August 19, 2000 - Undergoes more than five hours of surgery to remove two cancerous skin lesions on his temple and upper arm. The melanoma on his left arm is declared Stage 0, but the melanoma removed from McCain's left lower temple proves invasive, though later dissection of dozens of lymph nodes shows no evidence that the cancer had spread.
February 4, 2002 - McCain undergoes surgery to remove a skin lesion from the left side of his nose that doctors later say is a low-risk, early stage or "in situ" melanoma.
September 2002 - "Worth the Fighting for: A Memoir," is published.
November 2, 2004 - Is re-elected to the Senate for a fourth term.
February 28, 2007 - Appears on the "Late Show with David Letterman" and confirms that he will seek the Republican presidential nomination.
April 25, 2007 - While in New Hampshire, McCain announces he is running for president.
August 29, 2008 - Announces that he has selected Governor Sarah Palin of Alaska to be his vice presidential running mate.
September 4, 2008 - Accepts the Republican nomination for president at the Republican National Convention in St. Paul, Minnesota.
November 4, 2008 - Loses the presidential election to US Senator Barack Obama.
November 2, 2010 - Is re-elected to the Senate for a fifth term.
August 29, 2012 - Speaks at the 2012 Republican National Convention in Tampa, Florida, on his 76th birthday.
May 27, 2013 - Meets with rebels in Syria, making him the highest ranking elected official from the United States to visit since the conflict began in March 2011.
December 14, 2013 - McCain meets with opposition leaders in Kiev, Ukraine, during protests in the country.
November 8, 2016 - Wins his sixth term in the US Senate, defeating Democrat Ann Kirkpatrick.
July 15, 2017 - Mayo Clinic releases a statement that McCain had a blood clot removed from his left eye on July 14.
July 19, 2017 - Mayo Clinic doctors directly involved in the senator's care tell CNN McCain has been diagnosed with a primary glioblastoma, a type of brain tumor. Lab results from last week's surgery confirmed the presence of brain cancer associated with the blood clot.
July 25, 2017 - Returns to the Senate to cast his vote on a procedural step to advance Republicans' plans to repeal and replace the Affordable Care Act.
July 28, 2017 - Just before 2 a.m. ET, McCain votes "no," effectively killing his party's narrowly-crafted Obamacare repeal bill.
April 16, 2018 - McCain's office says that Senator McCain, who has been undergoing treatment for a brain cancer diagnosis since late 2017, is hospitalized in stable condition after undergoing surgery for an intestinal infection.
May 22, 2018 - McCain's memoir, "The Restless Wave: Good Times, Just Causes, Great Fights, and Other Appreciations," is published.
August 24, 2018 - McCain, who was diagnosed with brain cancer last year, has made the decision to discontinue medical treatment, according to a statement by the McCain family.
August 25, 2018 - Passes away at the age of 81.